Chief Financial Officer Alexander Dexne Leaves MediGene AG

Martinsried/Munich, May 8, 2007. The biotech company MediGene AG (Frankfurt, Prime Standard: MDG) announced that Chief Financial Officer Alexander Dexne will leave the company as from May 31, 2007. Alexander Dexne has been Chief Financial Officer of MediGene AG since May 2002. He has accepted a new position outside the biotech industry. Dr. Peter Heinrich, Chief Executive Officer of MediGene AG, comments: "Alexander Dexne resigns from his position very much to the executive and supervisory boards' regret. We would like to express our gratitude for his valuable contribution to our company. The supervisory board will soon appoint a qualified successor for the position of the Chief Financial Officer." This press release contains forward-looking statements that involve risks and uncertainties. The forward-looking statements contained herein represent the judgment of MediGene as of the date of this release. These forward-looking statements are no guarantees for future performance, and the forward-looking events discussed in this press release may not occur. MediGene disclaims any intent or obligation to update any of these forward-looking statements. MediGeneTM and the MediGeneTM Logo are trademarks of MediGene AG. - ends - MediGene AG is a publicly quoted (Frankfurt: Prime Standard: MDG) biotechnology company located in Martinsried/Munich, Germany, with subsidiaries in Oxford, UK and San Diego, USA. MediGene is the first German biotech company with a drug on the market. A second drug has been approved by the FDA. A third drug was recently inlicensed to market this drug in Europe. In addition, several drug candidates are currently in clinical development. MediGene also possesses innovative platform technologies. Contact MediGene AG: Email: Fax: ++49 - 89 - 85 65 - 2920 Julia Hofmann/Dr. Georg Dönges, Public Relations Tel.: ++49 - 89 - 85 65 - 3317 Dr. Michael Nettersheim, Investor Relations Tel.: ++49 - 89 - 85 65 - 2946 --- End of Message --- MediGene AG Lochhamer Strasse 11 Martinsried / München Germany WKN: 502090; ISIN: DE0005020903 ; Index: Prime All Share, CDAX, TECH All Share, HDAX, MIDCAP, TecDAX; Listed: Prime Standard in Frankfurter Wertpapierbörse, Freiverkehr in Bayerische Börse München, Freiverkehr in Börse Düsseldorf, Freiverkehr in Börse Stuttgart, Freiverkehr in Hanseatische Wertpapierbörse zu Hamburg, Freiverkehr in Niedersächsische Börse zu Hannover, Geregelter Markt in Frankfurter Wertpapierbörse;