Disclosure of shareholdings

Pursuant to article 21 sec 1 WpHG Deutsche Bank AG, Taunusanlage 12, 60325 Frankfurt, Germany has announced on July 25, 2007 to BB BIOTECH AG, Vordergasse 3, 8200 Schaffhausen, Switzerland that it decreased its holding in bearer shares BB BIOTECH AG as per July 19, 2007 to below 5% of the proportion of voting rights (4.98% / 1 189 126 voting rights). For further information please contact: Bellevue Asset Management AG, Seestrasse 16, 8700 Küsnacht, Switzerland Adrian Bruengger or Dr. Christian Lach, Tel. +41 44 267 67 00 --- End of Message --- BB BIOTECH AG Vordergasse 3 Schaffhausen Switzerland WKN: 888509; ISIN: CH0001441580; Index: SBIOM, IGSP, SLIFE; Listed: Investment Companies in SWX Swiss Exchange;